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Complete mitochondrial DNA profile in stroke: A geographical matched case-control study in Spanish population.

Mitochondrion - 1 Nov 2023

Onieva Ana, Martin Joan, R Cuesta-Aguirre Daniel, Planells Violeta, Coronado-Zamora Marta, Beyer Katrin, Vega Tomás, Lozano José Eugenio, Santos Cristina, Aluja Maria Pilar

Abstract excerpt

INTRODUCTION: Stroke, the second leading cause of death worldwide, is a complex disease influenced by many risk factors among which we can find reactive oxygen species (ROS). Since mitochondria are the main producers of cellular ROS, nowadays studies are trying to elucidate the role of these organelles and its DNA (mtDNA) variation in stroke risk. The aim of the present study was to perform a comprehensive...

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PMID: 37793469
DOI: 10.1016/j.mito.2023.10.001

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