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Article

The role of the cross-link His-Tyr in the functional properties of the binuclear center in cytochrome c oxidase.

The Journal of biological chemistry - 19 Apr 2002

Pinakoulaki Eftychia, Pfitzner Ute, Ludwig Bernd, Varotsis Constantinos

Abstract excerpt

Resonance Raman and Fourier transform infrared spectroscopies have been used to study the aa(3)-type cytochrome c oxidase and the Y280H mutant from Paracoccus denitrificans. The stability of the binuclear center in the absence of the Tyr(280)-His(276) cross-link is not compromised since heme a(3) retains the same proximal environment, spin, and coordination state as in the wild type enzyme in both the oxidized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11825904
DOI: 10.1074/jbc.M112200200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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