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Article

Is anisotropic propagation of polarized molecular distribution the common mechanism of swirling patterns of planar cell polarization?

Journal of theoretical biology - 7 Feb 2009

Zhu Hao

Abstract excerpt

Mutations in multiple planar cell polarity (PCP) genes can cause swirling patterns indicated by whorls and tufts of hairs in the wings and the abdomen of Drosophila and in the skin of vertebrates. Damaged global directional cue caused by mutations in four-jointed, fat, and dachsous, impaired cellular hexagonal packing caused by mutations in frizzled, or weakened intracellular signaling caused by mutations in...

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Identifiers

PMID: 18930066
DOI: 10.1016/j.jtbi.2008.08.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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