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Article

Prickle isoforms determine handedness of helical morphogenesis.

eLife - 14 Jan 2020

Cho Bomsoo, Song Song, Axelrod Jeffrey D

Abstract excerpt

Subcellular asymmetry directed by the planar cell polarity (PCP) signaling pathway orients numerous morphogenetic events in both invertebrates and vertebrates. Here, we describe a morphogenetic movement in which the intertwined socket and shaft cells of the Drosophila anterior wing margin mechanosensory bristles undergo PCP-directed apical rotation, inducing twisting that results in a helical structure of defined...

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Identifiers

PMID: 31934858
DOI: 10.7554/eLife.51456
PMCID: PMC7004564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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