Article
Maternal and fetal Toll-like receptor 4 genotype and chorionic plate inflammatory lesions.
American journal of obstetrics and gynecology - 1 Oct 2008
Simhan Hyagriv N, MacPherson Trevor, Caritis Steve N, Krohn Marijane A
Abstract excerpt
OBJECTIVE: The objective of the study was to explore the relation between maternal and fetal genetic variation in Toll-like receptor 4 (TLR4) and chorionic plate inflammation STUDY DESIGN: In this prospective observational cohort of 109 women with singleton gestations, 13 tag single nucleotide polymorphisms (SNPs) were genotyped in the TLR4 gene. The diagnosis of chorionic plate inflammation was made by a single...
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