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Article

Toll-like receptor 4 mediates intrauterine growth restriction after systemic Campylobacter rectus infection in mice.

Molecular oral microbiology - 1 Oct 2012

Arce R M, Caron K M, Barros S P, Offenbacher S

Abstract excerpt

Campylobacter rectus is associated with fetal exposure and low birthweight in humans. C. rectus also invades placental tissues and induces fetal intrauterine growth restriction (IUGR) in mice, along with overexpression of Toll-like receptors (TLR4), suggesting that TLR4 may mediate placental immunity and IUGR in mice. To test this hypothesis we examined the effect of in vitro TLR4 neutralization on trophoblastic...

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Identifiers

PMID: 22958386
DOI: 10.1111/j.2041-1014.2012.00651.x
PMCID: PMC3442926

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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