Article
Multiplex measurement of cytokine/receptor gene polymorphisms and interaction between interleukin-10 (-1082) genotype and chorioamnionitis in extreme preterm delivery.
Journal of the Society for Gynecologic Investigation - 1 Jul 2006
Kerk Julia, Dördelmann Michael, Bartels Dorothee B, Brinkhaus Maria-Jantje, Dammann Christiane E L, Dörk Thilo, Dammann Olaf
Abstract excerpt
OBJECTIVES: To establish a multiplex amplification refractory mutation system (ARMS) in fluid and dried whole blood, and to perform a pilot study to examine the role for single-nucleotide polymorphisms (SNPs) of inflammation-associated genes (interleukin [IL]-1 and -10, tumor necrosis factor-alpha [TNFA], and toll-like receptor-4 [TLR4]) and their interaction with clinical chorioamnionitis (CAM) in prematurity....
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