Article
Establishment of patient-derived non-small cell lung cancer xenografts as models for the identification of predictive biomarkers.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2008
Fichtner Iduna, Rolff Jana, Soong Richie, Hoffmann Jens, Hammer Stefanie, Sommer Anette, Becker Michael, Merk Johannes
Abstract excerpt
PURPOSE: It was the aim of our study to establish an extensive panel of non-small cell lung cancer (NSCLC) xenograft models useful for the testing of novel compounds and for the identification of biomarkers. EXPERIMENTAL DESIGN: Starting from 102 surgical NSCLC specimens, which were obtained from...
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