Article
alpha-Endosulfine is a conserved protein required for oocyte meiotic maturation in Drosophila.
Development (Cambridge, England) - 1 Nov 2008
Von Stetina Jessica R, Tranguch Susanne, Dey Sudhansu K, Lee Laura A, Cha Byeong, Drummond-Barbosa Daniela
Abstract excerpt
Meiosis is coupled to gamete development and must be well regulated to prevent aneuploidy. During meiotic maturation, Drosophila oocytes progress from prophase I to metaphase I. The molecular factors controlling meiotic maturation timing, however, are poorly understood. We show that Drosophila alpha-endosulfine (endos) plays a key role in this process. endos mutant oocytes have a prolonged prophase I and fail to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
