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Article

The C. elegans Myt1 ortholog is required for the proper timing of oocyte maturation.

Development (Cambridge, England) - 1 Feb 2006

Burrows Anna E, Sceurman Bonnielin K, Kosinski Mary E, Richie Christopher T, Sadler Penny L, Schumacher Jill M, Golden Andy

Abstract excerpt

Maturation promoting factor (MPF), a complex of cyclin-dependent kinase 1 and cyclin B, drives oocyte maturation in all animals. Mechanisms to block MPF activation in developing oocytes must exist to prevent precocious cell cycle progression prior to oocyte maturation and fertilization. This study sought to determine the developmental consequences of precociously activating MPF in oocytes prior to fertilization....

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Identifiers

PMID: 16421191
DOI: 10.1242/dev.02241
PMCID: PMC1794222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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