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Article

Genetics of diabetes. Trans-racial gene mapping studies.

Bailliere's clinical endocrinology and metabolism - 1 Jun 1991

Mijovic C H, Barnett A H, Todd J A

Abstract excerpt

A major component of inherited susceptibility to IDDM is associated with one or more loci in the MHC. Identification of the primary susceptibility genes has been complicated by the low frequency of recombination, i.e. linkage disequilibrium, within the MHC. It is difficult to distinguish whether a detected genetic association with the disease is primary, or secondary due to linkage disequilibrium with an allele...

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Identifiers

PMID: 1892469
DOI: 10.1016/s0950-351x(05)80130-2

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