Article
Molecular IDDM epidemiology: international studies. WHO DiaMond Molecular Epidemiology Sub-Project Group.
Diabetes research and clinical practice - 1 Oct 1996
Dorman J S, McCarthy B, McCanlies E, Kramer M K, Vergona R J, Stone R, Steenkiste A R, Kocova M, Trucco M
Abstract excerpt
The WHO DiaMond Molecular Epidemiology Sub-Project is testing the hypothesis that the geographic differences in IDDM incidence reflect population variation in the frequency of IDDM susceptibility genes (i.e., DQA1 and DQB1 alleles with sequences coding for arginine (R) in position 52 of the DQ alpha-chain, and an amino acid other than aspartic acid (ND) in position 57 of the DQ beta-chain, respectively) using a...
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