Article
HLA class II polymorphism in patients with type 1 diabetes mellitus from a Brazilian racially admixtured population.
Ethnicity & disease - 1 Jan 2009
Alves Crésio, Toralles Maria Betânia P, Carvalho Gildásio C
Abstract excerpt
BACKGROUND: Several studies have demonstrated a fundamental role for the histocompatibility antigens (ie, human leukocyte antigens or HLA) in the susceptibility of, or protection to, type 1 diabetes mellitus (T1DM). However, this has not been adequately studied in racially admixtured populations. OBJECTIVES: To assess the frequency of HLA class II (DQA1, DQB1 and DRB1) associated to susceptibility or protection...
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