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Article

Focal adhesion kinase controls aggressive phenotype of androgen-independent prostate cancer.

Molecular cancer research : MCR - 1 Oct 2008

Johnson Thomas R, Khandrika Lakshmipathi, Kumar Binod, Venezia Sarah, Koul Sweaty, Chandhoke Ryan, Maroni Paul, Donohue Robert, Meacham Randall B, Koul Hari K

Abstract excerpt

Overexpression of focal adhesion kinase (FAK) has been well correlated with tumor development and/or the maintenance of tumor phenotype. In addition, inappropriate activation of the extracellular regulated kinase (ERK) signaling pathway is common to many human cancers. In the present study, we in...

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Identifiers

PMID: 18922979
DOI: 10.1158/1541-7786.MCR-08-0052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18922979-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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