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Article

Signaling mechanisms that mediate invasion in prostate cancer cells.

Annals of the New York Academy of Sciences - 1 Dec 2004

Bonaccorsi L, Marchiani S, Muratori M, Carloni V, Forti G, Baldi E

Abstract excerpt

Recent evidence indicates that androgen-sensitive prostate cancer cells have a less malignant phenotype characterized by reduced migration and invasion. We investigated whether the presence of the androgen receptor could affect EGFR-mediated signaling by evaluating autotransphosphorylation of the receptor as well as activation of the downstream signaling pathway PI3K/AKT. Immunoprecipitation studies demonstrated...

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Source

Identifiers

PMID: 15650253
DOI: 10.1196/annals.1322.032

Genes

EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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