Article
Base mismatch-specific endonuclease activity in extracts from Saccharomyces cerevisiae.
Nucleic acids research - 11 Sept 1991
Chang D Y, Lu A L
Abstract excerpt
An endonuclease activity (called MS-nicking) for all possible base mismatches has been detected in the extracts of yeast, Saccharomyces cerevisiae. DNAs with twelve possible base mismatches at one defined position are cleaved at different efficiencies. DNA fragments with A/G, G/A, T/G, G/T, G/G, or A/A mismatches are nicked with greater efficiencies than C/T, T/C, C/A, and C/C. DNA with an A/C or T/T mismatch is...
Topics
- Base Composition
- Base Sequence
- DNA Repair
- Endodeoxyribonucleases
- Methylation
- Molecular Sequence Data
- Mutation
- Nucleic Acid Heteroduplexes
- Recombination, Genetic
- Saccharomyces cerevisiae