Article
DNA mismatch repair catalyzed by extracts of mitotic, postmitotic, and senescent Drosophila tissues and involvement of mei-9 gene function for full activity.
Molecular and cellular biology - 1 Mar 1998
Bhui-Kaur A, Goodman M F, Tower J
Abstract excerpt
Extracts of Drosophila embryos and adults have been found to catalyze highly efficient DNA mismatch repair, as well as repair of 1- and 5-bp loops. For mispairs T.G and G.G, repair is nick dependent and is specific for the nicked strand of heteroduplex DNA. In contrast, repair of A.A, C.A, G.A, C...
Topics
- Adenine
- Animals
- Catalysis
- Cellular Senescence
- Cytosine
- DNA Repair
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Guanine
- HeLa Cells
- Humans
- Insect Proteins
- Male
- Mitosis
- Mutation
- Nickel