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Article

SP6 RNA polymerase stutters when initiating from an AAA... sequence.

Nucleic acids research - 11 Sept 1991

Cunningham P R, Weitzmann C J, Ofengand J

Abstract excerpt

The 16S ribosomal RNA gene of Escherichia coli was placed under the transcriptional control of consensus and modified T7 promoters and a modified SP6 promoter. Both T7 and SP6 polymerases faithfully transcribed the coding sequence (beginning at the +1 position) of each construct, although SP6 polymerase was five-fold more effective than T7 polymerase in initiating with the AAAUUG... sequence. An appreciable...

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Identifiers

PMID: 1891358
DOI: 10.1093/nar/19.17.4669
PMCID: PMC328707

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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