Article
Lack of a relationship between the polymorphism of debrisoquine oxidation and lung cancer.
British journal of clinical pharmacology - 1 May 1991
Duche J C, Joanne C, Barre J, de Cremoux H, Dalphin J C, Depierre A, Brochard P, Tillement J P, Bechtel P
Abstract excerpt
1. Determination of debrisoquine oxidation phenotype was carried out in 119 healthy subjects, 135 patients with chronic bronchitis and 153 patients with lung cancer, all of Caucasian origin. 2. A non-Gaussian distribution of the log D/HD ratio was observed in the three groups. 3. Assuming an antimode of 1.12, the proportion of PMs was found to be 6.7% in healthy subjects, 8.9% in chronic bronchitics and 6.5% in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.