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Changes in nuclear morphology and size in mammalian temperature-sensitive mutants.

Cell structure and function - 11 Apr 2026

Sugaya Kimihiko

Abstract excerpt

Nuclear morphology alters during development and disease. Nuclear size and shape are regulated through several mechanisms. In this study, details of phenotypes of temperature-sensitive mutants, which were isolated from Chinese hamster CHO-K1 cells to identify genes responsible for the maintenance of chromosome integrity, were characterized with particular focus on changes in their nuclear size and shape. DNA...

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PMID: 41833374
DOI: 10.1247/csf.26002

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