Article
Genetic variation in the ASIC3 gene influences blood pressure levels in Taiwanese.
Journal of hypertension - 1 Nov 2008
Ko Yu-Lin, Hsu Lung-An, Wu Semon, Teng Ming-Sheng, Chang Hsien-Hsun, Chen Chih-Cheng, Cheng Ching-Feng
Abstract excerpt
BACKGROUND: The acid-sensing ion channel 3 (ASIC3) is a ligand-gated cation channel activated by extracellular protons, and is associated with an exercise-induced pressor reflex and possibly autonomic imbalance. METHODS: To test the statistical association between genetic polymorphisms of the ASIC3 gene and blood pressure (BP) variations in Taiwanese, 551 unrelated individuals (286 men and 265 women) were...
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