Article
Association of C825T polymorphism of G protein beta3 subunit with the autonomic nervous system in young healthy Japanese individuals.
American journal of hypertension - 1 Apr 2005
Matsunaga Tetsuro, Nagasumi Kae, Yamamura Tsubasa, Gu Ning, Nishikino Mariko, Ueda Yukihiko, Moritani Toshio, Aoki Norihiko, Tsuda Kinsuke, Yasuda Koichiro
Abstract excerpt
BACKGROUND: The T allele of the C825T polymorphism of the G protein beta3 subunit gene (GNB3) is reported to be associated with increased intracellular signal transduction and the prevalence of essential hypertension. Because the two major receptors in the autonomic nervous system (ANS), the adrenergic and muscarinic acetylcholine receptors, are G protein-coupled receptors, it was expected that the GNB3 C825T...
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