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Article

Ambulatory blood pressure is associated with polymorphic variation in P2X receptor genes.

Hypertension (Dallas, Tex. : 1979) - 1 Nov 2008

Palomino-Doza Julian, Rahman Thahira J, Avery Peter J, Mayosi Bongani M, Farrall Martin, Watkins Hugh, Edwards Christopher R W, Keavney Bernard

Abstract excerpt

The P2X receptor gene family encodes a series of proteins that function as ATP-gated nonselective ion channels. P2X receptor channels are involved in transducing aldosterone-mediated signaling in the distal renal tubule and are potential candidate genes for blood pressure regulation. We performed a family based quantitative genetic association study in 248 families ascertained through a proband with hypertension...

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Source

Identifiers

PMID: 18852390
DOI: 10.1161/HYPERTENSIONAHA.108.113282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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