Article
Association of circadian genes with diurnal blood pressure changes and non-dipper essential hypertension: a genetic association with young-onset hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Feb 2015
Leu Hsin-Bang, Chung Chia-Min, Lin Shing-Jong, Chiang Kuang-Mao, Yang Hsin-Chou, Ho Hung-Yun, Ting Chih-Tai, Lin Tsung-Hsien, Sheu Sheng-Hsiung, Tsai Wei-Chuan, Chen Jyh-Hong, Yin Wei-Hsian, Chiu Ting-Yu, Chen Chin-Iuan, Fann Cathy Sj, Chen Yuan-Tsong, Pan Wen-Harn, Chen Jaw-Wen
Abstract excerpt
Recent studies have suggested that circadian genes have important roles in maintaining the circadian rhythm of the cardiovascular system. However, the associations between diurnal BP changes and circadian genes remain undetermined. We conducted a genetic association study of young-onset hypertension, in which 24-h ambulatory blood pressure (BP) monitoring was performed. A total of 23 tag single-nucleotide...
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