Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma potassium level is associated with common genetic variation in the beta-subunit of the epithelial sodium channel.

American journal of physiology. Regulatory, integrative and comparative physiology - 1 Mar 2008

Gaukrodger Nicole, Avery Peter J, Keavney Bernard

Abstract excerpt

Plasma potassium is a moderately heritable phenotype, but no robust associations between common single nucleotide polymorphisms (SNPs) and plasma potassium have previously been described. Genetic influences on renal potassium handling could be important in the etiology of hypertension. We have tested whether common genetic variation in the gene encoding the beta-subunit of the epithelial sodium channel (SCNN1B)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldosterone
Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Sodium Channels

Share to Heterozygote

Share to Homozygote

Share to Hypertension

Share to Introns

Share to Potassium

Source

Identifiers

PMID: 18184758
DOI: 10.1152/ajpregu.00732.2007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma potassium level is associated with common genetic variation in the beta-subunit of the epithelial sodium channel.PMID 18184758Read ↗

Rare Variants in Genes Encoding Subunits of the Epithelial Na+ Channel Are Associated With Blood Pressure and Kidney Function.Semantic proximity Read ↗

Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population.Semantic proximity Read ↗

Polymorphisms in the WNK1 gene are associated with blood pressure variation and urinary potassium excretion.Semantic proximity Read ↗

Resequencing Epithelial Sodium Channel Genes Identifies Rare Variants Associated With Blood Pressure Salt-Sensitivity: The GenSalt Study.Semantic proximity Read ↗

Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.Semantic proximity Read ↗

Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation to plasma renin and aldosterone levels in essential hypertension.Semantic proximity Read ↗

Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population.Semantic proximity Read ↗

Association of ATP1B1 single-nucleotide polymorphisms with blood pressure and hypertension in a Chinese population.Semantic proximity Read ↗

Associations of epithelial sodium channel genes with blood pressure: the GenSalt study.Semantic proximity Read ↗

Association of Genetic Variation in the Epithelial Sodium Channel Gene with Urinary Sodium Excretion and Blood Pressure.Semantic proximity Read ↗

The R563Q mutation of the epithelial sodium channel beta-subunit is associated with hypertension.Semantic proximity Read ↗

Human epithelial Na+ channel missense variants identified in the GenSalt study alter channel activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.