Article
Genotypic resistance analysis of the virological response to fosamprenavir-ritonavir in protease inhibitor-experienced patients in CONTEXT and TRIAD clinical trials.
Antimicrobial agents and chemotherapy - 1 Dec 2008
Marcelin Anne-Geneviève, Flandre Philippe, Molina Jean-Michel, Katlama Christine, Yeni Patrick, Raffi Francois, Antoun Zeina, Ait-Khaled Mounir, Calvez Vincent
Abstract excerpt
The aim of this study was to identify human immunodeficiency virus (HIV) protease mutations associated with virological response (VR) to fosamprenavir-ritonavir (FPV/r) in 113 protease inhibitor (PI)-experienced patients randomized in both CONTEXT and TRIAD clinical trials and receiving the same dose (700/100 mg twice daily) of FPV/r. The impact of each protease mutation on the VR to FPV/r, defined as the...
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