Article
Clinically validated mutation scores for HIV-1 resistance to fosamprenavir/ritonavir.
The Journal of antimicrobial chemotherapy - 1 Jun 2008
Masquelier B, Assoumou K L, Descamps D, Bocket L, Cottalorda J, Ruffault A, Marcelin A G, Morand-Joubert L, Tamalet C, Charpentier C, Peytavin G, Antoun Z, Brun-Vézinet F, Costagliola D
Abstract excerpt
BACKGROUND: We developed clinically relevant genotypic scores for resistance to fosamprenavir/ritonavir in HIV-1 protease inhibitor (PI)-experienced patients. METHODS: PI-experienced patients with virological failure receiving fosamprenavir/ritonavir as the sole PI for at least 3 months and with detectable fosamprenavir plasma levels were included. The impact of baseline protease mutations on virological response...
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