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Article

Simple algorithm derived from a geno-/phenotypic database to predict HIV-1 protease inhibitor resistance.

AIDS (London, England) - 18 Aug 2000

Schmidt B, Walter H, Moschik B, Paatz C, van Vaerenbergh K, Vandamme A M, Schmitt M, Harrer T, Uberla K, Korn K

Abstract excerpt

BACKGROUND: Resistance against protease inhibitors (PI) can either be analysed genotypically or phenotypically. However, the interpretation of genotypic data is difficult, particularly for PI, because of the unknown contributions of several mutations to resistance and cross-resistance. OBJECTIVE: Development of an algorithm to predict PI phenotype from genotypic data. METHODS: Recombinant viruses containing...

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PMID: 10985309
DOI: 10.1097/00002030-200008180-00007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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