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Article

Mutations associated with virological response to darunavir/ritonavir in HIV-1-infected protease inhibitor-experienced patients.

The Journal of antimicrobial chemotherapy - 1 Mar 2009

Descamps Diane, Lambert-Niclot Sidonie, Marcelin Anne-Geneviève, Peytavin Gilles, Roquebert Bénédicte, Katlama Christine, Yeni Patrick, Felices Mathieu, Calvez Vincent, Brun-Vézinet Françoise

Abstract excerpt

OBJECTIVE: The aim of the study was to identify a pattern of protease gene mutations associated with the virological response to darunavir/ritonavir-based regimens. PATIENTS AND METHODS: We analysed 153 treatment-experienced patients receiving a darunavir/ritonavir salvage regimen as a sole protease inhibitor (PI). Virological response was defined as an HIV-1 RNA load of <200 copies/mL at month 3. The impact of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Drug Resistance, Viral

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Share to HIV Protease Inhibitors

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Source

Identifiers

PMID: 19147519
DOI: 10.1093/jac/dkn544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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