Article
In-depth characterization of the microRNA transcriptome in a leukemia progression model.
Genome research - 1 Nov 2008
Kuchenbauer Florian, Morin Ryan D, Argiropoulos Bob, Petriv Oleh I, Griffith Malachi, Heuser Michael, Yung Eric, Piper Jessica, Delaney Allen, Prabhu Anna-Liisa, Zhao Yongjun, McDonald Helen, Zeng Thomas, Hirst Martin, Hansen Carl L, Marra Marco A, Humphries R Keith
Abstract excerpt
MicroRNAs (miRNAs) have been shown to play important roles in physiological as well as multiple malignant processes, including acute myeloid leukemia (AML). In an effort to gain further insight into the role of miRNAs in AML, we have applied the Illumina massively parallel sequencing platform to carry out an in-depth analysis of the miRNA transcriptome in a murine leukemia progression model. This model simulates...
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