Article
Bioinformatic tools for microRNA dissection.
Nucleic acids research - 8 Jan 2016
Akhtar Most Mauluda, Micolucci Luigina, Islam Md Soriful, Olivieri Fabiola, Procopio Antonio Domenico
Abstract excerpt
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory networks. MiRNAs are endogenous single-stranded non-coding RNAs (~22-nt long) that regulate gene expression at the post-transcriptional level. Through pairing with mRNA, miRNAs can down-regulate gene expression by inhibiting translation or stimulating mRNA degradation. In some cases they can also up-regulate the expression of a...
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