Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Classification of pediatric acute myeloid leukemia based on miRNA expression profiles.

Oncotarget - 16 May 2017

Obulkasim Askar, Katsman-Kuipers Jenny E, Verboon Lonneke, Sanders Mathijs, Touw Ivo, Jongen-Lavrencic Mojca, Pieters Rob, Klusmann Jan-Henning, Michel Zwaan C, van den Heuvel-Eibrink Marry M, Fornerod Maarten

Abstract excerpt

Pediatric acute myeloid leukemia (AML) is a heterogeneous disease with respect to biology as well as outcome. In this study, we investigated whether known biological subgroups of pediatric AML are reflected by a common microRNA (miRNA) expression pattern. We assayed 665 miRNAs on 165 pediatric AML samples. First, unsupervised clustering was performed to identify patient clusters with common miRNA expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Enhancer-Binding Proteins
Share to Chromosome Inversion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Gene Regulatory Networks

Share to Leukemia, Myeloid, Acute

Share to MicroRNAs

Share to Nucleophosmin

Share to Translocation, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 28380436
DOI: 10.18632/oncotarget.16525
PMCID: PMC5464851

Genes

NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Classification of pediatric acute myeloid leukemia based on miRNA expression profiles.PMID 28380436Read ↗

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemiaSemantic proximity Read ↗

RNA-seq–based miRNA signature as an independent predictor of relapse in pediatric B-cell acute lymphoblastic leukemiaSemantic proximity Read ↗

MicroRNA expression profiling in relation to the genetic heterogeneity of acute myeloid leukemiaSemantic proximity Read ↗

MicroRNA Patterns Associated with Clinical Prognostic Parameters and CNS Relapse Prediction in Pediatric Acute LeukemiaSemantic proximity Read ↗

Gene expression profiling of pediatric acute myelogenous leukemiaSemantic proximity Read ↗

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia.Semantic proximity Read ↗

Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators.Semantic proximity Read ↗

DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)Semantic proximity Read ↗

Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosisSemantic proximity Read ↗

Integrated epigenetic and genetic analysis identifies markers of prognostic significance in pediatric acute myeloid leukemiaSemantic proximity Read ↗

MicroRNAs as New Biomarkers for Diagnosis and Prognosis, and as Potential Therapeutic Targets in Acute Myeloid LeukemiaSemantic proximity Read ↗

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.