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Article

The relationship of photoreceptor degeneration to retinal vascular development and loss in mutant rhodopsin transgenic and RCS rats.

Experimental eye research - 1 Dec 2008

Pennesi Mark E, Nishikawa Shimpei, Matthes Michael T, Yasumura Douglas, LaVail Matthew M

Abstract excerpt

The early loss of photoreceptors in some retinal degenerations in mice has been shown to have a profound effect on vascular development of the retina. To better characterize this relationship, we have examined the formation of retinal blood vessels during the first month of life in 8 lines of transgenic rats with different ages of onset and rates of photoreceptor cell loss mediated by the expression of mutant...

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Share to Neovascularization, Pathologic
Share to Photoreceptor Cells, Vertebrate

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Share to Rats, Transgenic

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Share to Retinal Pigment Epithelium

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Source

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Identifiers

PMID: 18848932
DOI: 10.1016/j.exer.2008.09.004
PMCID: PMC3541029

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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