Article
Neovascularization of the RPE: temporal differences in mice with rod photoreceptor gene defects.
Experimental eye research - 1 Nov 1998
Nishikawa S, LaVail M M
Abstract excerpt
Neovascularization (NV) of the retinal pigment epitheium (RPE) by retinal capillaries following degeneration and loss of photoreceptor cells is a widely recognized phenomenon in rodents. NV of the RPE usually occurs several weeks to months after the loss of photoreceptor cells. We have observed that NV of the RPE occurs much earlier in a line of P23H mutant rhodopsin transgenic mice than in most other mice and...
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