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Article

Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes.

Investigative ophthalmology & visual science - 1 Aug 2016

Liu Haitao, Tang Jie, Du Yunpeng, Saadane Aicha, Tonade Deoye, Samuels Ivy, Veenstra Alex, Palczewski Krzysztof, Kern Timothy S

Abstract excerpt

PURPOSE: Loss of photoreceptor cells is associated with retinal vascular degeneration in retinitis pigmentosa, whereas the presence of photoreceptor cells is implicated in vascular degeneration in diabetic retinopathy. To investigate how both the absence and presence of photoreceptors could damage the retinal vasculature, we compared two mouse models of photoreceptor degeneration (opsin-/- and RhoP23H/P23H ) and...

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Source

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Identifiers

PMID: 27548901
DOI: 10.1167/iovs.16-19415
PMCID: PMC5015983

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ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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