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Article

Temporal requirement of RPE‐derived VEGF in the development of choroidal vasculature

8 Jan 2010

Abstract excerpt

Vascular endothelial growth factor (VEGF-A or VEGF) is a potent growth factor for the development of retinal and choroidal vasculatures. To define the temporal requirement of the retinal pigmented epithelium (RPE)-derived VEGF in choroidal vascular development, we generated conditional VEGF knockout mice using an inducible Cre/lox system. The loss of the RPE-derived VEGF was confirmed with immunoblotting and...

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PMID: 20067573
DOI: 10.1111/j.1471-4159.2010.06573.x

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