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Article

Cooperation of sumoylated chromosomal proteins in rDNA maintenance.

PLoS genetics - 1 Oct 2008

Takahashi Yoshimitsu, Dulev Stanimir, Liu Xianpeng, Hiller Natalie Jasmin, Zhao Xiaolan, Strunnikov Alexander

Abstract excerpt

SUMO is a posttranslational modifier that can modulate protein activities, interactions, and localizations. As the GFP-Smt3p fusion protein has a preference for subnucleolar localization, especially when deconjugation is impaired, the nucleolar role of SUMO can be the key to its biological functions. Using conditional triple SUMO E3 mutants, we show that defects in sumoylation impair rDNA maintenance, i.e., the...

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Share to Chromosomal Proteins, Non-Histone
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Protein Processing, Post-Translational

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Source

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Identifiers

PMID: 18846224
DOI: 10.1371/journal.pgen.1000215
PMCID: PMC2563031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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