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A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental Hematopoiesis

9 Oct 2008

Abstract excerpt

Although it is clear that telomerase expression is crucial for the maintenance of telomere homeostasis, there is increasing evidence that the TERT protein can have physiological roles that are independent of this central function. To further examine the role of telomerase during vertebrate development, the zebrafish telomerase reverse transcriptase (zTERT) was functionally characterized. Upon zTERT knockdown,...

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PMID: 18846223
DOI: 10.1371/journal.pone.0003364

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A Non-Canonical Function of Zebrafish Telomerase Reverse Transcriptase Is Required for Developmental HematopoiesisPMID 18846223Read ↗

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