Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice.

Neuroreport - 29 Oct 2008

Quintero Gabriel C, Spano Daniela, Lahoste Gerald J, Harrison Laura M

Abstract excerpt

Dopamine activates five different receptor subtypes and a complex array of intracellular signaling pathways. Rhes is a striatally expressed guanidine triphosphate-binding protein involved in dopamine signaling. Here we have used mutant mice to test whether Rhes (Ras homolog enriched in striatum) is involved in D1 and D2 dopamine receptor-mediated behaviors. Rhes was not necessary for the expression of normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzazepines
Share to Dopamine Agonists
Share to Dopamine Antagonists

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Grooming

Share to Injections, Intraperitoneal

Share to Receptors, Dopamine D1

Share to Space Flight

Share to Stereotyped Behavior

Source

Open in PubMed Open full text

Identifiers

PMID: 18845937
DOI: 10.1097/WNR.0b013e3283118434
PMCID: PMC2649821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Ras homolog Rhes affects dopamine D1 and D2 receptor-mediated behavior in mice.PMID 18845937Read ↗

Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.Semantic proximity Read ↗

The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.Semantic proximity Read ↗

Rhes influences striatal cAMP/PKA-dependent signaling and synaptic plasticity in a gender-sensitive fashion.Semantic proximity Read ↗

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice.Semantic proximity Read ↗

PKA modulates iron trafficking in the striatum via small GTPase, Rhes.Semantic proximity Read ↗

Global Rhes knockout in the Q175 Huntington's disease mouse model.Semantic proximity Read ↗

Dopamine receptor functions: lessons from knockout mice [corrected].Semantic proximity Read ↗

Altered striatal function in a mutant mouse lacking D1A dopamine receptors.Semantic proximity Read ↗

Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's diseaseSemantic proximity Read ↗

Huntington’s Disease is a disorder of the corpus striatum: Focus on Rhes (Ras homologue enriched in the striatum)Semantic proximity Read ↗

Mice lacking dopamine D4 receptors are supersensitive to ethanol, cocaine, and methamphetamine.Semantic proximity Read ↗

Asymmetric elevation of striatal dopamine D2 receptors in the chakragati mouse: neurobehavioral dysfunction in a transgenic insertional mutant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.