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Article

The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.

Molecular and cellular neurosciences - 1 Feb 2008

Errico Francesco, Santini Emanuela, Migliarini Sara, Borgkvist Anders, Centonze Diego, Nasti Valentina, Carta Manolo, De Chiara Valentina, Prosperetti Chiara, Spano Daniela, Herve Denis, Pasqualetti Massimo, Di Lauro Roberto, Fisone Gilberto, Usiello Alessandro

Abstract excerpt

Rhes is a small GTP-binding protein prominently localized in the striatum. Previous findings obtained in cell culture systems demonstrated an involvement of Rhes in cAMP/PKA signalling pathway, at a level proximal to the activation of heterotrimeric G-protein complex. However, its role in the striatum has been, so far, only supposed. Here we studied the involvement of Rhes in dopaminergic signalling, by employing...

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Identifiers

PMID: 18035555
DOI: 10.1016/j.mcn.2007.10.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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