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Article

Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy.

Science (New York, N.Y.) - 14 Nov 2008

Keller Philipp J, Schmidt Annette D, Wittbrodt Joachim, Stelzer Ernst H K

Abstract excerpt

A long-standing goal of biology is to map the behavior of all cells during vertebrate embryogenesis. We developed digital scanned laser light sheet fluorescence microscopy and recorded nuclei localization and movement in entire wild-type and mutant zebrafish embryos over the first 24 hours of development. Multiview in vivo imaging at 1.5 billion voxels per minute provides "digital embryos," that is, comprehensive...

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PMID: 18845710
DOI: 10.1126/science.1162493

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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