Article
Three-dimensional microCT imaging of mouse development from early post-implantation to early postnatal stages.
Developmental biology - 15 Nov 2016
Hsu Chih-Wei, Wong Leeyean, Rasmussen Tara L, Kalaga Sowmya, McElwee Melissa L, Keith Lance C, Bohat Ritu, Seavitt John R, Beaudet Arthur L, Dickinson Mary E
Abstract excerpt
In this work, we report the use of iodine-contrast microCT to perform high-throughput 3D morphological analysis of mouse embryos and neonates between embryonic day 8.5 to postnatal day 3, with high spatial resolution up to 3µm/voxel. We show that mouse embryos at early stages can be imaged either within extra embryonic tissues such as the yolk sac or the decidua without physically disturbing the embryos. This...
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