Quantitative Geometric Modeling of Blood Cells from X-ray Histotomograms of Whole Zebrafish Larvae

Abstract excerpt

Tissue phenotyping is foundational to understanding and assessing the cellular aspects of disease in organismal context and an important adjunct to molecular studies in the dissection of gene function, chemical effects, and disease. As a first step toward computational tissue phenotyping, we explore the potential of cellular phenotyping from 3-Dimensional (3D), 0.74 µm isotropic voxel resolution, whole zebrafish l...

Topics

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• Bone and Bones
• Craniofacial Abnormalities
• Environment
• Genomics
• Image Processing, Computer-Assisted
• Models, Animal
• Phenotype
• Zebrafish

Identifiers and source

Literature Corpus work

dd4f45e2-bad4-554d-b05e-f30115be8561

DOI

10.1101/2023.05.23.541939