Article
Thermodynamics and folding pathway of tetraloop receptor-mediated RNA helical packing.
Journal of molecular biology - 19 Dec 2008
Vander Meulen Kirk A, Davis Jared H, Foster Trenton R, Record M Thomas, Butcher Samuel E
Abstract excerpt
Little is known about the thermodynamic forces that drive the folding pathways of higher-order RNA structure. In this study, we employ calorimetric [isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC)] and spectroscopic (NMR and UV) methods to characterize the therm...
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