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Article

Thermodynamics of trimer-of-hairpins formation by the SIV gp41 envelope protein.

Journal of molecular biology - 23 Mar 2001

Jelesarov I, Lu M

Abstract excerpt

The gp41 envelope protein mediates the entry of primate immunodeficiency viruses into target cells by promoting the fusion of viral and cellular membranes. The structure of the gp41 ectodomain core represents a trimer of identical helical hairpins in which a central trimeric coiled-coil made up of three amino-terminal helices is wrapped in an outer layer of three antiparallel carboxyl-terminal helices. Triggering...

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Identifiers

PMID: 11254387
DOI: 10.1006/jmbi.2001.4469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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