Article
The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae.
BMC evolutionary biology - 7 Oct 2008
Obbard Darren J, Callister Deborah M, Jiggins Francis M, Soares Dinesh C, Yan Guiyun, Little Tom J
Abstract excerpt
BACKGROUND: Host-parasite coevolution can result in balancing selection, which maintains genetic variation in the susceptibility of hosts to parasites. It has been suggested that variation in a thioester-containing protein called TEP1 (AGAP010815) may alter the ability of Anopheles mosquitoes to transmit Plasmodium parasites, and high divergence between alleles of this gene suggests the possible action of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.