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Article

An Evolution-Based Screen for Genetic Differentiation between Anopheles Sister Taxa Enriches for Detection of Functional Immune Factors.

PLoS pathogens - 1 Dec 2015

Mitri Christian, Bischoff Emmanuel, Takashima Eizo, Williams Marni, Eiglmeier Karin, Pain Adrien, Guelbeogo Wamdaogo M, Gneme Awa, Brito-Fravallo Emma, Holm Inge, Lavazec Catherine, Sagnon N'Fale, Baxter Richard H, Riehle Michelle M, Vernick Kenneth D

Abstract excerpt

Nucleotide variation patterns across species are shaped by the processes of natural selection, including exposure to environmental pathogens. We examined patterns of genetic variation in two sister species, Anopheles gambiae and Anopheles coluzzii, both efficient natural vectors of human malaria in West Africa. We used the differentiation signature displayed by a known coordinate selective sweep of immune genes...

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Identifiers

PMID: 26633695
DOI: 10.1371/journal.ppat.1005306
PMCID: PMC4669117

Genes

TEP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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