Article
Anopheles immune genes and amino acid sites evolving under the effect of positive selection.
PloS one - 26 Jan 2010
Parmakelis Aristeidis, Moustaka Marina, Poulakakis Nikolaos, Louis Christos, Slotman Michel A, Marshall Jonathon C, Awono-Ambene Parfait H, Antonio-Nkondjio Christophe, Simard Frederic, Caccone Adalgisa, Powell Jeffrey R
Abstract excerpt
BACKGROUND: It has long been the goal of vector biology to generate genetic knowledge that can be used to "manipulate" natural populations of vectors to eliminate or lessen disease burden. While long in coming, progress towards reaching this goal has been made. Aiming to increase our understanding regarding the interactions between Plasmodium and the Anopheles immune genes, we investigated the patterns of genetic...
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