Article
Adaptive divergence between incipient species of Anopheles gambiae increases resistance to Plasmodium.
Proceedings of the National Academy of Sciences of the United States of America - 4 Jan 2011
White Bradley J, Lawniczak Mara K N, Cheng Changde, Coulibaly Mamadou B, Wilson Michael D, Sagnon N'Fale, Costantini Carlo, Simard Frederic, Christophides George K, Besansky Nora J
Abstract excerpt
The African malaria mosquito Anopheles gambiae is diversifying into ecotypes known as M and S forms. This process is thought to be promoted by adaptation to different larval habitats, but its genetic underpinnings remain elusive. To identify candidate targets of divergent natural selection in M and S, we performed genomewide scanning in paired population samples from Mali, followed by resequencing and genotyping...
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