Article
Dissecting the genetic basis of resistance to malaria parasites in Anopheles gambiae.
Science (New York, N.Y.) - 2 Oct 2009
Blandin Stephanie A, Wang-Sattler Rui, Lamacchia Marina, Gagneur Julien, Lycett Gareth, Ning Ye, Levashina Elena A, Steinmetz Lars M
Abstract excerpt
The ability of Anopheles gambiae mosquitoes to transmit Plasmodium parasites is highly variable between individuals. However, the genetic basis of this variability has remained unknown. We combined genome-wide mapping and reciprocal allele-specific RNA interference (rasRNAi) to identify the genom...
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